Toluene oel. Avoid inhalation, contact with eyes, skin and clothing.

Aspiration hazardThe liquid content is classified as Cat 1 aspiration hazard. It evaporates quickly. Each entry shows a substance or a group of substances or a substance in a mixture, and the consequent restriction conditions. (1) Exposure usually occurs to a mixture of toluene 2,4- and 2,6-diisocyanate, and not to the individual The RfC for toluene was derived from a series of 10 studies observing neurological effects in workers. What is the result in mg/m3 3. LOTUS - the natural products occurrence database. It can be found in our schools, offices, homes, automobiles and other enclosed environments. Methods All data for the study were obtained from 1,705 occupational health examination and evaluation reports from 2013 to 2017, and a 1910. OEL. (2) The measures to be taken shall include the provision and use Dec 31, 2018 · Toluene indicated the lowest hazard quotient, whilst ethylbenzene was potentially found to have the highest hazard quotient, at a value of 0. 05 L) and Ceiling sampling 5 min (0. ! short-term health chemical and biological. ChEBI. 7 mg/kg, median 3. If mean levels and duration of exposure corresponding to seg-ments of various jobs can be measured or estimated, then an overall exposure concentratio. 1000 TABLE Z-2, TABLE Z-2. The Jun 15, 2004 · Potential effects of human occupational exposures to toluene on colour vision were investigated in a follow-up study over 4 years with three repeated examinations. Where substances have been classified as carcinogens, mutagens or asthmagens, to comply with the Control of Substances The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of toluene. Toluene is used in the manufacture of benzoic acid, benzaldehyde, explosives, dyes and many other organic compounds. Use in a well-ventilated area. Lgs. 1 Precautions for safe handling: Use in a chemical fume hood, with air supplied by an independent system. oided evenwhere duration is short or work intensity is light. In EU the average content of toluene in petrol is about 11 %. Can cause effects as described for inhalation. Exposure above OEL-M should be a. a. TRANSPORT INFORMATION DOT UN-No UN1294 Proper Shipping Name TOLUENE Hazard Class 3 Packing Group II TDG UN-No UN1294 Proper Shipping Name TOLUENE Hazard Class 3 Packing Group II IATA UN-No UN1294 Proper Shipping Name TOLUENE Hazard Class 3 Packing Group II IMDG/IMO UN-No UN1294 Proper Shipping Name TOLUENE Hazard Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. Jan 11, 2024 · Toluene is a simple benzene derivative also known as methylbenzene, phenylmethane, or toluol. Computed by PubChem 2. Exposure to toluene may occur from breathing ambient or indoor air affected by such. 957: Besley and Bottomley, 1974: Coefficents calculated by NIST from author's data. Can be absorbed through the skin. Phase diagram included. 14) Dates. 89: 4. 31 A benchmark dose Toluene. 13 to 297. These documents provide information on the health effects of exposure, the chemical’s toxicity and material for responding to a chemical incident. Colorless to pale-yellow solid or liquid (above 71°F) with a sharp, pungent odor. Toluene was first isolated by Pierre-Joseph Pelletier (1788–1842) and Philippe Walter (1810–1847) in 1837. 4 mm Hg at 25 oC. 1- and 2-fold of the currently valid MAK values and occupational exposure For the health-based OEL, the analysis assumed that a practical population-averaged threshold resides below the observable range in epidemiologic data, and applying uncertainty factors to an estimate of some point of departure (PoD) in the observable range is a reasonable approach for estimating a safe level of exposure. Toluene, C6 H5 -CH3, is a clear colorless liquid, highly flammable with a sweet, pungent aromatic odor. 4 × 10 2, respectively. Please indicate on the 91A which of these compounds are known to be present. The acetone OEL is 50 mg/m 3. Apr 1, 2002 · The WG critically reviewed and discussed the strengths and weaknesses of the available published information describing the effects of toluene in animals and humans, to assess its adequacy as a potential point of departure for the establishment of an OEL for toluene and to derive an OEL. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. Occupational exposure limits are one tool or method used in this process. drowsiness. Apr 6, 2021 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. Create: 2005-03-26. Sep 14, 2023 · OEL is the occupational exposure limit in ppm. Environmental Protection Agency (EPA) identifies the Toluene. 1 ng/mL for 2,6-toluenediamine (Tinnerberg and Mattsson 2008). 584-84-9) Documentation for Immediately Dangerous to Life or Health Concentrations (IDLHs) This publication documents the criteria and information sources that have been used by NIOSH to determine immediately dangerous to life or health concentrations (IDLHs). 162/2007 Italia - Valores límite de exposición profesional Nombre local Toluene OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm Comentarios pelle Referencia normativa Allegato XXXVIII del D. Toluene diisocyanate is produced commercially as an 80:20 (2,4-toluene diisocyanate:2,6-toluene diisocyanate) mixture of the two isomers. A severe exposure can cause unconsciousness. 1. Although small levels can be found in the outdoor air as an industrial chemical or in vehicular exhaust, indoor air levels are typically Jan 31, 2012 · 1 Summary. most workers can be exposed to, day. 162/2007 Italie - Valeurs Limites d'exposition professionnelle Nom local Toluene OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm Remarque pelle Référence réglementaire Allegato XXXVIII del D. Modify: 2024-07-13. In homes, toluene may be found in paint Toluene is a clear, colorless liquid with a distinctive smell. 1 Packing Group II 15. Oct 14, 2022 · Toluene is a gasoline additive that can be used to improve octane ratings for fuel used in race cars and other automobiles. Toluene is less dense than water and will float on Toluene is an ototoxic chemical according to rat studies: inhalation exposure in the presence of noise may lead to cochlear impairment. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic Toluene diisocyanate exists in two isomeric forms (2,4-toluene diisocyanate and 2,6-toluene diisocyanate) which have similar properties and effects. 5 hr. El tolueno se genera en el proceso de producción de gasolina y otros combustibles a partir del petróleo crudo, y al producir coque de carbón. 3-ethyltoluene is a derivative of toluene bearing an additional ethyl substituent at position 3. 1 Packing Group II IMDG/IMO UN-No UN2078 Proper Shipping Name TOLUENE DIISOCYANATE Hazard Class 6. Including a reference to "substitution" in the hierarchy of controls in Regulation 833. Mar 7, 2024 · Introduction Considering the adverse carcinogenic and non-carcinogenic health effects of Volatile Organic Compounds (VOC) and specially Benzene, Toluene, Ethylbenzene and Xylenes (BTEX) which are widely used in vehicle manufacturing industry, it is clear that monitoring and control of occupational exposure to these substances is of utmost significance. urces. The mean current exposures were 26±21 ppm for Toluene. Component ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL (TWA) Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m 3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m TWA: 20 ppm Legend ACGIH - American Conference of Governmental Dec 11, 2023 · Toluene causes irritation of the eyes and nose, muscle fatigue, and tingling of the skin. Toluene - Thermophysical Properties. 2005-03-26. 1990, Reg. Oils and other products of the distillation of high temperature coal tar; similar products in which the weight of the aromatic constituents exceeds that of the non-aromatic constituents. The Committee also recommended a skin notation to indicate that the dermal 3. Symptoms include pain, redness, and swelling. Sep 28, 2023 · A volume of 0. Toluene is also highly flammable and may catch on fire if exposed to heat or flames. • Example: diethylamine, TLV: – 8-hour is 5 ppm. Because the VHR for benzene is higher that the VHR for toluene sampling in this example should be conducted for benzene. 2 ng/mL for 2,4-toluenediamine and 62. 05. The Lower Olefins and Aromatics (LOA) REACH Consortium, which includes toluene registrants in the EU, established a Working Group (WG) to conduct a review of the occupational exposure limit (OEL) for toluene. 867 g/mL and vapor pressure of 28. Published 1 July 2014. , 1991 May 1, 2000 · Toluene is a representative VOC commonly found in Chinese dwellings. View Unit 5. In the air, toluene can only incompletely burn and the flame is yellow. 1) is a colorless, non-corrosive, flammable liquid with an aromatic odor similar to that of benzene. PUBLIC HEALTH STATEMENT FOR TOLUENE. Toluene-2,4-diisocyanate. Registration number Chemical name CAS-No. Existe de forma natural en el petróleo crudo y en el bálsamo de Tolú. These fact sheets summarize the information on occurrence and health effects of the chemicals covered, presenting guideline values where these have been derived and the basis for The OSHA PELs for toluene are 200 ppm, the NIOSH REL is 100 ppm, the ACGIH TLV is 20 ppm, and the Cal-OSHA PEL is 10 ppm—a twenty-fold range. m. Toluene has a pungent odour, a boiling point of 110. Long-term exposure may cause liver and kidney damage (OSHA, 2019). Synonyms & Trade Names Methyl benzene, Methyl benzol, Phenyl methane, Toluol CAS No. R. Avoid the formation of dust and aerosols. Related Information. The addition of a new listing and OEL for diesel particulate matter in the Ontario Table (Table 1) in Regulation 833. 1/4 for edema were reported across all 6 animals. In a document issued on 12 June 2001, the CSTEE commented on the results of the Risk Assessment of Toluene, carried out in the framework of Council regulation (EEC) 793/93 on the evaluation and control of the risks of existing substances. Toluene is less dense than water and is slightly soluble in water . May 10, 2024 · Occupational hygiene uses the techniques of anticipation, identification, evaluation, and control to identify and evaluate exposure. To calculate the minimum sampling time required to detect concentrations at the OELs listed in the table, we can use the following formula: Sampling time = (OEL x V) / (C x Q) Where: OEL = 50 ppm (ACGIH 8-hour TWA TLV) Apr 20, 2023 · The OEL for toluene is 200 parts per million (ppm) over an 8-hour workday or 400 ppm for a 15-minute time-weighted average. It is also called methylbenzene, indicating that a methyl group has been added to one of benzene’s carbon atoms. Avoid inhalation, contact with eyes, skin and clothing. EC-No. It is flammable at temperatures greater than 40°F (4. Occupational Exposure Limits (OEL) Adjustment Tool. 8). El tolueno es un líquido transparente e incoloro con un olor característico. Modify: 2024-07-06. 859; CP 25; Methacide; Methylbenzene; Methylbenzol; NCI-C07272; Phenylmethane; Toluol Abstract: Objective This study was designed to conduct a retrospective and systematic occupational health risk assessment (OHRA) of enterprises that used benzene, toluene, and xylene (BTX) in Shanghai, China. Toluene-2,4-diisocyanate, 80%, remainder 2,6-diisocyanate Revision Date 31-Mar-2024 Packing Group II IATA UN-No UN2078 Proper Shipping Name TOLUENE DIISOCYANATE Hazard Class 6. These are values set to prevent occupational diseases, notably in personnel exposed to harmful chemicals in the workplace. Reagent-grade toluene is available with a purity of greater than 99% (Aldrich Chemical Co. A sampling pump is run for 8 hours at 12. The central nervous system (CNS) is the primary target organ for toluene toxicity in both humans and animals for acute (short-term) and chronic (long May 10, 2024 · Symptoms may include headache, nausea, dizziness, drowsiness, and confusion. after day without harm to their health. Sep 9, 2018 · 5. O. 02 ppm: Ca See Appendix A: TOLUENE DIISOCYANATE, 2,4- OR 2,6- (OR AS A MIXTURE) - ACGIH: o-Toluidine: 95-53-4: 5: 22: 2 ppm: Ca See Appendix A: o-TOLUIDINE - ACGIH: Toxaphene; see the amount of chemical in the air that. pdf from HEALTH CAR MOS 6301 at Columbia Southern University. 1020, Access to employee exposure and medical records. 81 e s. Scientific Committee for Toxicity and Ecotoxicity (CSTEE) opinion 2001. R. shift and 40-hour work week. It is a colorless, volatile liquid with a special aroma. (A draft toxicological profile proposes Toluene-2,4-diisocyanate (TDI) (CAS No. Here, the company remains compliant with the OSHA mandatory exposure limitation. 005 ppm (ST) 0. 162/2007 Italy - Occupational Exposure Limits Local name Toluene OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm Remark pelle Occupational exposure to 2,4-toluene diisocyanate can occur for those workers involved in its manufacture . 75 L) ****120 min (6 L) Toluene: 108-88-3: See Annotated Z-2: See Annotated Z-2: TOLUENE - ACGIH: Toluene-2,4-diisocyanate (TDI) 584-84-9 (C) 0. OEL for exposure to mixture of chemical substances. Using the Raoult's law and Dalton's law equations, maximum ambient air concentration of toluene at the 300 mg/m 3 OEL for the blend is approximately 45 mg/m 3. , Citation 2017) Substances restricted under REACH. 02 (C) 0. What is the detection limit for this procedure? OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm OEL STEL 384 mg/m³ OEL STEL [ppm] 100 ppm Regulatory reference Π. 1 L/min x 1 ppm) = 400 minutes. TDI, 2,4-TDI, 2,4-Toluene diisocyanate. The toluene sample result fell below the OSHA standard, although it exceeded the ACGIH limitation. 5 °C, and a vapour pressure of 3 kPa at 20 °C. It is important to use proper ventilation when working with toluene and appropriate PPE to reduce the risk of toluene exposure. Component ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL (TWA) Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m 3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m TWA: 50 ppm TWA: 188 mg/m3 Legend for 8 hours a day, 40 hours a week under a. The Permissible Exposure Limit for toluene is 200 ppm 8-hour time weighted average, with an acceptable ceiling concentration of 300 ppm and an acceptable peak over the ceiling concentration of 500 ppm over 10 minutes. The review focussed on CNS and neuro-behavioural toxicity, ototoxicity, effects on colour vision, reproductive and Dec 3, 2020 · of 31 January 2017 establishing a fourth list of indicative occupational exposure limit values pursuant to Council Directive 98/24/EC, and amending Commission Directives 91/322/EEC, 2000/39/EC and 2009/161/EU (Text with EEA relevance) Toluene is an organic solvent and is a constituent of various fuel streams from petrochemical refining. OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm OEL STEL 384 mg/m³ OEL STEL [ppm] 100 ppm Regulatory reference Π. juiːn / ), also known as toluol ( / ˈtɒl. Description. It dissolves other substances easily and evaporates quickly into the air. May 18, 2022 · Chapter 12 of the Guidelines for drinking-water Quality (GDWQ) includes fact sheets on chemical contaminants, based on comprehensive review documents published by WHO. oderate work-load. Methylisocyanate (MIC) (CAS No. OEL-M values listed in Table I-1 and I-2 are applicable in cases where the substance exists alone. Toluene. Toluene is marketed principally as nitration and industrial grades, its purity being dependent on the specific gravity and boiling range of the product (Hoff, 1983). It occurs naturally in crude oil and in the tolú tree. Toluene is found naturally in crude oil, and is used in oil refining and the manufacturing of paints, lacquers, explosives (TNT) and glues. Toluene (C6H5CH3; MW = 92. 4-Ethyltoluene is a natural product found in Gossypium hirsutum and Carica papaya with data available. See annual publication for most recent information. The U. 162/2007 Italy - Occupational Exposure Limits Local name Toluene OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm Remark pelle May 1, 2023 · However, an excursion limits derived from a 20 ppm OEL (60–100 ppm) would be at lower end of the range for NOAECs identified above. The goal is to identify solutions for eliminating or reducing the hazard, and monitoring to ensure no further harm occurs. Causes moderate to severe irritation. The CDC Agency for Toxic Substances and Disease Registry (ATSDR) established an Acute Minimal Risk Level (MRL) of 2 ppm and a Chronic MRL of 1 ppm in 2017. Jul 1, 2014 · Details. 5 Personal samples should be collected as toluene exposure is expected to vary between workers due to TOLUENE: ICSC: 0078 (October 2002) Methylbenzene Toluol Phenylmethane: CAS #: 108-88-3: EU-OEL: 192 mg/m 3, 50 ppm as TWA; 384 mg/m 3, 100 ppm as STEL; (skin) Tolu-enediamine, a metabolite of toluene diisocyanate, has been measured in the plasma at levels up to 27. This method permits the determination of gaseous monomeric diisocyanates, such as 4,4'-methylene diphenyl diisocyanate (MDI), 1,6-hexamethylene diisocyanate (HDI), isophorone diisocyanate (IPDI), 1,5-naphthylene diisocyanate (NADI), and 2,4- and 2,6-toluene diisocyanate (TDI) in a concentration range between 0. Toluene is used in these applications because it is dense and contains significant energy per unit of Workplace exposure limits. Toluene, also known as methylbenzene or phenylmethane, is one of the most frequently found VOCs in our indoor air. 1910. More often than not the studies on 1. It is based on working an 8-hour work. Nov 28, 2023 · Toluene is a clear, flammable, aromatic hydrocarbon liquid with a smell similar to benzene. It's a colorless liquid with a sweet smell and taste. Therefore, the minimum sampling time required is 400 minutes or approximately 6. See attachments below for more information on this proposal. 1-20. OEL TWA [ppm] 50 ppm OEL STEL 384 mg/m³ OEL STEL [ppm] 100 ppm Référence réglementaire Π. (8-hour TWA OEL will be a lower concentration) 14 OELs • Short Term Exposure Limits – Exposures above 8-hour OEL but below STEL • Should not be longer than 15 minutes • Should not occur more than 4 times per day • There should be at least 60 minutes between exposures in this range. workers when assessing. 96-111. at or above 200°F. 1294 Toluene - 108-88-3 U220 - 14. It is a colorless, water -insoluble liquid with the odor associated with paint thinners. Toluene is a common ingredient in degreasers. Chemical, physical and thermal properties of toluene, also called methylbenzene, toluol and phenylmethane. Marquez Sanford Columbia Southern University Unit V Hazard Occupational Exposure Limits (OEL)s Manganese Fume 5 mg/m3 (OSHA Product Name : TrusTec™ Toluene Reference, Fuel Grade Material : 1016965, 1016964, 1016968, 1016967, 1016963, 1016966 EC-No. 5 and 8 ppm, and is irritating at 750 ppm (Henderson, 2001). As an employer, you must protect workers from exposure to hazardous substances, including dust, fumes, chemicals, vapours, mists, nanotechnology, gases, biological agents and germs that cause disease. It is used in the extraction of various principles from plants. 108-88-3 RTECS No. 20. (1) The general public may be exposed to 2,4-toluene diisocyanate through emissions from urethane foam production facilities. Swedish workers manufacturing polyurethane products excreted 53. Toluene is produced in the process of making gasoline and other fuels from crude oil and in making coke from coal. The critical health effect underpinning the IOELV-STEL for toluene was human neurological changes reported at high exposures, with data supporting a NOAEC of 80 ppm (300 mg/m3) for 4. It is composed of >10% Cat 1 substances and the kinematic viscosity is <20. 10. Regulatory information United States of America Abstract. 2 (PubChem release 2021. 3-Ethyltoluene is a natural product found in Camellia sinensis, Gossypium hirsutum, and Carica papaya with data available. 08 ppm. 833, s. Skin Contact: SKIN IRRITANT. Antisal 1A; Anisen; Caswell No. , 1988). NIOSH: Alert -Preventing asthma and death from diisocyanate exposure. This Public Health Statement summarizes the Agency for Toxic Substances and Disease Registry’s (ATSDR) findings on toluene, including chemical characteristics, exposure risks, possible health effects from exposure, and ways to limit exposure. The odor threshold for toluene ranges between 2. OEL – Occupational Exposure Limit is the airborne concentration of a compound to which nearly all workers can be repeatedly be exposed to for 8 hours a day, 40 hours a week, without adverse effects. 5 L/min pulling air through activated charcoal which will absorb the toluene. The indoor concentration is thought to be around 10 mg/m 3. 78) was found between the time weighted toluene exposure during a five day working week (range 8-416 mg/cu m, median 75) and the concentration of toluene in subcutaneous adipose tissue (range 1. 2707. Jul 13, 2017 · Considering the relatively low ACGIH TLV for toluene, it is important that we consider whether the ambient air concentrations at the calculated OEL do not exceed this value. 25 L) ***STEL sampling 15 min (0. El tolueno es un buen solvente (una sustancia que OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm OEL STEL 384 mg/m³ OEL STEL [ppm] 100 ppm Referencia normativa Π. Avoid prolonged or repeated exposure. 5 mL of undiluted toluene was applied under occlusive conditions for 4 hours and an irritation response was measured at 1, 24, 48 and 72 hours, and 7, 14 and 21 days after patch removal. and use. It is also used as a solvent for paints, lacquers, gums, and resins and as a thinner for inks, perfumes, and dyes. The ACGIH has an exposure limit for toluene of 100 ppm as an 8-hour TWA and 150 ppm as a 15-minute STEL; NIOSH Toluene ( / ˈtɒl. Regulatory information United States of America CAS Number 108-88-3 Synonym. lvent. problems like irritation or substances. The detection limit for the activated charcoal is 20 mg. The results presented in our study indicate that there is a lower probability of non-carcinogenic health effects as a result of exposure to domestic coal combustion technology, as described in this study. 6 nmol of toluenediamine per gram of creatinine (Bolognesi et al Toluene is a clear, colorless, volatile liquid with a sweet, pungent, benzene-like odor. 02 ppm (C) 0. (based on the model and guide developed by the Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST)) Brought to you by OHCOW, and the Occupational Disease Action Plan Contributors, this tool* allows the calculation of the adjusted workplace exposure limit for an Minimum sampling time = (OEL x TWA period) / (sampling rate x D) where: Minimum sampling time = (50 ppm x 8 hours) / (0. ju. 108-88-3. P. 1996. 624-83-9) The charcoal tubes should also be blank tested before use to ensure that they are free from contamination. 00 001. 9 × 10 4 and 1. Legal Entity Registration number Toluene 108-88-3 203-625-9 601-021-00-3 Chevron Phillips Chemicals International NV 01-2119471310-51-0116 Toluene 108-88-3 Temperature (K) A B C Reference Comment; 273. Index No. In the case of toluene, it appears a 100 ppm STEL would be protective based on available human data. The analytical laboratory report 78 µg of Hexane on the sorbent tube. S. The lowest reported LOAEC provided a simulated blood toluene concentration of 0. 7. The higher the octane number or rating, the greater the fuel’s resistance to knocking or pinging during combustion. Using the vapor pressures and occupational exposure limits (8-hour TWA PEL) provided above for benzene and toluene yields VHRs of 9. Beyond this, the EPA reference concentration (RfC) is 5 mg/m3 (equivalent to 1. 23679: 1426. A sample is taken for 10 hours and 03 minutes at 47 ml/min. In a group of 37 rotogravure printers a close correlation (rs = 0. 4°C); therefore, it is a significant fire hazard at room temperature. In the United States, the American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Values (TLV) and the OSHA Permissible Exposure Limit (PEL) standards are the most cited contaminant airborne standards (Cruz et al. Example 2 Toluene-2,4-diisocyanate, 80%, remainder 2,6-diisocyanate Revision Date 31-Mar-2024 Packing Group II IATA UN-No UN2078 Proper Shipping Name TOLUENE DIISOCYANATE Hazard Class 6. Toxicokinetic information indicated that since the steady-state level of toluene in blood was achieved after exposures of around 25 min of exposure, a 15 min exposure to 100 ppm (384 mg/m3) would not lead to Jun 15, 2022 · Chemical reference number (CAS): 108-88-3. The table below is the Annex XVII to REACH and includes all the restrictions adopted in the framework of REACH and the previous legislation, Directive 76/769/EEC. After the identification of some of toluene’s molecular actions, several research groups studied metabolic and neurochemical changes associated with toluene exposure. SummaryToluene is added to gasoline, used to produce benzene, and used as a. 8/4) for erythema and 2. May 9, 2023 · The EU Scientific Committee on Occupational Exposure Limits (SCOEL) established an indicative OEL value for toluene in 2001, composed of an 8-h Time Weighted Average (TWA) value of 50 ppm and a 15-min Short Term Exposure Limit (STEL) of 100 ppm ( SCOEL, 2001 ). CAS: 108-88-3; Chemical Formula: C 6 H 5 CH 3. When workers are exposed to a mixture of chemical substances and there is no reliable evidence to the contrary that the effects of the chemicals are assumed to be additive, the effects should 3. 7 hours. DOT ID & Guide. 3 (2. analytical laboratory report 219 µg of Toluene on the sorbent tube. 448-45. 14: 0. 5 mm2/s at 40 °C. Colour vision was measured with the Lanthony desaturated colour vision test D-15d, and the colour confusion index (CCI) was calculated. There is no need to contact SLTC before sampling. DHHS (NIOSH) Publication No. Class IIIB Combustible Liquid: Fl. i. Toluene is an aromatic hydrocarbon with narcotic and neurotoxic effects and, like all inhalants, has the potential to induce addiction Component ACGIH TLV OSHA PEL NIOSH Mexico OEL (TWA) Toluene TWA: 20 ppm (Vacated) TWA: 100 ppm (Vacated) TWA: 375 mg/m3 Ceiling: 300 ppm (Vacated) STEL: 150 ppm (Vacated) STEL: 560 mg/m 3 TWA: 200 ppm IDLH: 500 ppm TWA: 100 ppm TWA: 375 mg/m3 STEL: 150 ppm STEL: 560 mg/m TWA: 20 ppm Legend ACGIH - American Conference of Governmental Industrial Feb 1, 2008 · Recent studies in printeries have found evidence that concentrations of toluene and styrene below the OEL, when combined with noise below recommended limits, can have ototoxic effects (Chang et al OEL TWA 192 mg/m³ OEL TWA [ppm] 50 ppm OEL STEL 384 mg/m³ OEL STEL [ppm] 100 ppm Référence réglementaire Π. Δ. 75 L) ****120 min (6 L) Toluene Safety in the Workplace Toluene, also known as “methylbenzene”, “phenylmethane” or “toluol” is a clear, colorless liquid with a sweet smell. 7 mg/L (Echeverria et al. A within-subject experiment was conducted to compare working memory performance and electroencephalographic patterns of participants exposed to toluene at 70 ppb (Tol group), a WHO-recommended toluene exposure limit, and at 0 ppb (Ctrl group) in a controlled environment chamber. It is used in making paints, paint Apr 5, 2024 · Toluene, sec-Butyl Acetate, Benzene and Isobutyl Alcohol all have/are known interferences. As a volatile solvent, misuse or abuse is common, resulting in an acute toxidrome. 4. Toluene is a good solvent (a substance that can dissolve other substances). The former OSHA standard for toluene was 200 ppm as an 8-hour TWA limit, with a 300-ppm ceiling (not to be exceeded for more than 10 minutes in any eight-hour period), and a 500-ppm peak. 3. Last updated 16 . Apr 19, 2021 · ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Toluene diisocyanate, 2,4 or 2,6- (or as a mixture). A sample is taken for 6 hours and 14 minutes at 101 ml/min. Keep away from sources of ignition. 3 (1). The water solubility is about 580 mg/L. Toluene has a density of 0. XS5250000. 3 ppm), and the ATSDR minimal risk level (MRL) for chronic exposure is 0. 2 to 259. Toluene is a member of aromatic hydrocarbons. Related Pages. The toxicological review provides information on which these values are based. For example, using microPET, [ 84] it has been shown that acute and repeated toluene exposure markedly reduces metabolic function in rat brain. *80 min (4L) **Peak sampling 1 min (0. Toluene mixes readily with many organic solvents, but is poorly soluble in water. Chronic low-level occupational or industrial exposure to toluene can cause toxicity. Mean scores (24, 48 and 72 hours) of ≥ 2. Toluene (molecular formula: C7H8) is a homologue of benzene, also known as "methyl benzene" and "phenyl methane". 9 aprile 2008, n. Technical grades (90–120°C boiling range) are less pure and may contain up to 25% benzene as well as other hydrocarbons (Clement Apr 25, 2019 · Most countries now have occupational exposure limits (OEL) for BTEX at the workplace. What is the result in mg/m3 2. (1) Every employer shall take all measures reasonably necessary in the circumstances to protect workers from exposure to a hazardous biological or chemical agent because of the storage, handling, processing or use of such agent in the workplace. - Toluol (toluene) CONTAINING TOLUENE MORE THAN 75% w/w BUT LESS THAN 95% w/w. ɒl, - ɔːl, - oʊl / ), is a substituted aromatic hydrocarbon [15] with the chemical formula C6H5CH3, often abbreviated as PhCH3, where Ph stands for phenyl group. lj nu mg lp md ds bm hb uc de